I don't have an e-reader and don't particularly want one, although I think they're brilliant for holidays and long train/plane journeys (speaking as someone who's had to pay excess baggage for taking loads of books on holiday ), however I sit and look at a screen all day so don't really want to look at one when I'm reading for pleasure as well, although if George R R Martin ever finishes the 6th Game of Thrones novel then I might give in and get one just to read that, as it will probably be a huge book
I've heard they're also really good for people who can't hold a book easily, a friend of mine has very bad arthritis and finds it hard to hold a book and turn the pages, so for him it's brilliant. I think there is a place for them, but I prefer a real book, and find it easier to look back through a real book too, especially if I want to refer to a family tree.