yes! I had this problem last week with a book, I made it all the way to page 200 of a fairly tedious book (it was all about nuclear weapons, I thought computers had a lot of acronyms but they are nothing compared to this) just because every 20 or so pages it had some obscure but interesting nugget, it would have been put down by page 20 if not.
In general I will give a book a good try, I always like to give it about 2-3 chapters to get going, otherwise I put it away with a marker in it.